Trichoplein
WebApr 23, 2012 · Trichoplein disappears from the basal body in quiescent cells. (A) RPE1 cells were stained with antitrichoplein (Tricho.), anti-Odf2, and anti–Centrin 2. Bottom micrograph is shown with an illustration, which indicates the structure of a mother or daughter centriole (MC or DC) with the appendage (Ap) and orientations. WebApr 1, 2012 · Trichoplein shows a low degree of sequence similarity to trichohyalin, plectin, and myosin heavy chain, and colocalizes with CK8/18 filaments in HeLa cells . Trichoplein may be involved in the organization of the apical network of keratin filaments and desmosomes in simple epithelial cells . Albatross ...
Trichoplein
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WebMay 22, 2015 · Trichoplein negatively regulates ciliogenesis at mother centrioles, controls recruitment of microtubules to centrioles, and may play a role in maintenance of … WebSep 26, 2016 · Instead, trichoplein depletion results in the elevation of p27 , one of CKIs (Fig. 2). P27 is known to increase during quiescent state but decrease during proliferation state [ 82 , 83 ]. Since CDK activities are also critical for the G0/G1 transition through the phosphorylation of pRb (the product of the retinoblastoma tumor suppressor gene) [ 89 – …
WebNX_Q9BT92 - TCHP - Trichoplein keratin filament-binding protein - Function. Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell … WebMar 21, 2024 · The encoded protein functions in ciliogenesis by acting as a substrate adaptor for the cullin3-based ubiquitin-conjugating enzyme E3 ligase, and targets trichoplein, a keratin-binding protein, for degradation via polyubiquitinylation. A mutation in this gene is associated with autosomal dominant myoclonic dystonia 26. [provided by RefSeq, Nov …
WebApr 30, 2012 · Trichoplein or Aurora A knockdown failed to induce ciliogenesis or cell cycle arrest in HeLa cells, which, like many cancerous cell types, have a reduced tendency to form primary cilia. “We're now investigating whether Aurora A knockdown has different effects in various normal and cancer cell lines,” says Inagaki. WebTrichoplein disappears from the basal body in quiescent cells. (A) RPE1 cells were stained with antitrichoplein (Tricho.), anti-Odf2, and anti–Centrin 2. Bottom micrograph is shown …
WebMar 15, 2011 · Trichoplein – a widely expressed keratin intermediate filament scaffold protein – is shown by Masaki Inagaki and co-workers on page 857 to have a key role in …
WebThe centrosomal protein trichoplein (TCHP) has been shown to promote cell cycle progression in the G 1-S phase by disassembling cilia. In this study, we showed that deletion of TCHP not only prevented the progression to the S phase but also resulted in cell cycle exit and entrance into G 0 phase. front brake drums for a 1965 mustangWebMar 21, 2024 · GeneCards Summary for TCHP Gene. TCHP (Trichoplein Keratin Filament Binding) is a Protein Coding gene. Diseases associated with TCHP include … ghost calls from my phoneWebAutophagy is an evolutionarily conserved and tightly regulated process that plays an important role in maintaining cellular homeostasis. It involves regulation of various genes that function to degrade unnecessary or dysfunctional cellular components, and to recycle metabolic substrates. Autophagy is modulated by many factors, such as nutritional … ghost call spiel exampleWebtrichoplein (G-2): sc-515025 Santa Cruz Biotechnology, Inc. 1.800.457.3801 831.457.3800 fax 831.457.3801 Europe +00800 4573 8000 49 6221 4503 0 www.scbt.com … ghost calls filmWebtrichoplein Antibodies. Santa Cruz Biotechnology, Inc. offers a broad range of trichoplein antibodies. Select trichoplein antibodies from monoclonal antibodies listed below. View … frontbrakeleverreplaceforducatiscrambler2022WebNdel1, a protein located at the subdistal appendage of mother centriole, functions as an upstream regulator of the trichoplein–Aurora A pathway that suppresses ciliogenesis in proliferating cells. (PDF) Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein–Aurora A pathway Tohru Kiyono - Academia.edu front brain drawingWebTchp trichoplein, keratin filament binding 77832 Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A 12683 Ifng interferon gamma 15978 Ppara peroxisome proliferator activated receptor alpha 19013 Itpr1 inositol 1,4,5-trisphosphate receptor 1 16438 Apoc2 apolipoprotein C-II 11813 ghost calls post malone dirty